PHARMACOPŒIAL DOSES.

Estimation of Doses and Integrated Doses

5.

Pneumococcal conjugate vaccine: are 3 doses equal to 4 doses?

After the introduction of routine infant immunization with 7-valent pneumococcal conjugate vaccine (PCV-7), the United States has witnessed a 74% decline in the number of children ,5 years of age diagnosed with invasive pneumococcal disease (IPD) and a 30% decline among all age groups. Likewise, rates of pneumoniaand otitis media-related medical visits among children, hospitalizations for pneum...

Methadone Induction Doses

Purpose: To review the literature on methadone deaths and propose evidencebased dosing guidelines. Methods: A literature search was conducted on overdose deaths during the induction phase. Data on methadone deaths from the Ontario coroner’s office, as well as prescribing guidelines from different countries and jurisdictions, were reviewed. The information was collectively considered and, using ...

Paludrine: Changes in the Doses

Accelerator boundary doses and skyshine.

Beginning this year, AEC contractors are being required to submit dose evaluations as low as 1.7 mrem per year to the surrounding public from their installations. This small incremental dose exists within the framework of a natural background of about 130 mrem per year. Some of the pitfalls in estimating these small doses, especially with regard to skyshine, are discussed. It is shown that, for...